An outbreak of 2009 pandemic influenza A (H1N1) virus infection in an elementary school in Pennsylvania.

TitleAn outbreak of 2009 pandemic influenza A (H1N1) virus infection in an elementary school in Pennsylvania.
Publication TypeJournal Article
Year of Publication2011
AuthorsMarchbanks TL, Bhattarai A, Fagan RP, Ostroff S, Sodha SV, Moll ME, Lee BY, Chang C-CH, Ennis B, Britz P, Fiore A, Nguyen M, Palekar R, W Archer R, Gift TL, Leap R, Nygren BL, Cauchemez S, Angulo FJ, Swerdlow D
Corporate AuthorsPennsylvania Working Group
JournalClin Infect Dis
Volume52 Suppl 1
Date Published2011 Jan 1
KeywordsAdolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Disease Outbreaks, Female, Humans, Infant, Infant, Newborn, Infection Control, Influenza A Virus, H1N1 Subtype, Influenza, Human, Interviews as Topic, Male, Middle Aged, Pennsylvania, Schools, Young Adult

In May 2009, one of the earliest outbreaks of 2009 pandemic influenza A virus (pH1N1) infection resulted in the closure of a semi-rural Pennsylvania elementary school. Two sequential telephone surveys were administered to 1345 students (85% of the students enrolled in the school) and household members in 313 households to collect data on influenza-like illness (ILI). A total of 167 persons (12.4%) among those in the surveyed households, including 93 (24.0%) of the School A students, reported ILI. Students were 3.1 times more likely than were other household members to develop ILI (95% confidence interval [CI], 2.3-4.1). Fourth-grade students were more likely to be affected than were students in other grades (relative risk, 2.2; 95% CI, 1.2-3.9). pH1N1 was confirmed in 26 (72.2%) of the individuals tested by real-time reverse-transcriptase polymerase chain reaction. The outbreak did not resume upon the reopening of the school after the 7-day closure. This investigation found that pH1N1 outbreaks at schools can have substantial attack rates; however, grades and classrooms are affected variably. Additional study is warranted to determine the effectiveness of school closure during outbreaks.

Alternate JournalClin. Infect. Dis.
PubMed ID21342888
PubMed Central IDPMC3738229
Grant ListU54 GM088491 / GM / NIGMS NIH HHS / United States
U60/CCU007277 / / PHS HHS / United States
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