The potential economic value of a hookworm vaccine.

TitleThe potential economic value of a hookworm vaccine.
Publication TypeJournal Article
Year of Publication2011
AuthorsLee BY, Bacon KM, Bailey R, Wiringa AE, Smith KJ
JournalVaccine
Volume29
Issue6
Pagination1201-10
Date Published2011 Feb 1
ISSN1873-2518
KeywordsAdolescent, Adult, Ancylostomatoidea, Animals, Brazil, Child, Cost-Benefit Analysis, Female, Hookworm Infections, Humans, Vaccines
Abstract

Hookworm infection is a significant problem worldwide. As development of hookworm vaccine proceeds, it is essential for vaccine developers and manufacturers, policy makers, and other public health officials to understand the potential costs and benefits of such a vaccine. We developed a decision analytic model to evaluate the cost-effectiveness of introducing a hookworm vaccine into two populations in Brazil: school-age children and non-pregnant women of reproductive age. Results suggest that a vaccine would provide not only cost savings, but potential health benefits to both populations. In fact, the most cost-effective intervention strategy may be to combine vaccine with current drug treatment strategies.

DOI10.1016/j.vaccine.2010.12.004
Alternate JournalVaccine
PubMed ID21167860
PubMed Central IDPMC3038553
Grant List1U54GM088491-0109 / GM / NIGMS NIH HHS / United States
U54 GM088491 / GM / NIGMS NIH HHS / United States
U54 GM088491-02 / GM / NIGMS NIH HHS / United States
Publication Categories: