Economic value of norovirus outbreak control measures in healthcare settings.

TitleEconomic value of norovirus outbreak control measures in healthcare settings.
Publication TypeJournal Article
Year of Publication2011
AuthorsLee BY, Wettstein ZS, McGlone SM, Bailey RR, Umscheid CA, Smith KJ, Muder RR
JournalClin Microbiol Infect
Volume17
Issue4
Pagination640-6
Date Published2011 Apr
ISSN1469-0691
KeywordsCaliciviridae Infections, Computer Simulation, Cross Infection, Disease Outbreaks, Gastroenteritis, Health Care Costs, Health Facilities, Humans, Infection Control, Norovirus
Abstract

Although norovirus is a significant cause of nosocomial viral gastroenteritis, the economic value of hospital outbreak containment measures following identification of a norovirus case is currently unknown. We developed computer simulation models to determine the potential cost-savings from the hospital perspective of implementing the following norovirus outbreak control interventions: (i) increased hand hygiene measures, (ii) enhanced disinfection practices, (iii) patient isolation, (iv) use of protective apparel, (v) staff exclusion policies, and (vi) ward closure. Sensitivity analyses explored the impact of varying intervention efficacy, number of initial norovirus cases, the norovirus reproductive rate (R(0)), and room, ward size, and occupancy. Implementing increased hand hygiene, using protective apparel, staff exclusion policies or increased disinfection separately or in bundles provided net cost-savings, even when the intervention was only 10% effective in preventing further norovirus transmission. Patient isolation or ward closure was cost-saving only when transmission prevention efficacy was very high (≥ 90%), and their economic value decreased as the number of beds per room and the number of empty beds per ward increased. Increased hand hygiene, using protective apparel or increased disinfection practices separately or in bundles are the most cost-saving interventions for the control and containment of a norovirus outbreak.

DOI10.1111/j.1469-0691.2010.03345.x
Alternate JournalClin. Microbiol. Infect.
PubMed ID20731684
PubMed Central IDPMC3005527
Grant List1U54GM088491-0109 / GM / NIGMS NIH HHS / United States
U54 GM088491 / GM / NIGMS NIH HHS / United States
U54 GM088491-01 / GM / NIGMS NIH HHS / United States
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