A computer simulation of vaccine prioritization, allocation, and rationing during the 2009 H1N1 influenza pandemic.

TitleA computer simulation of vaccine prioritization, allocation, and rationing during the 2009 H1N1 influenza pandemic.
Publication TypeJournal Article
Year of Publication2010
AuthorsLee BY, Brown ST, Korch GW, Cooley PC, Zimmerman RK, Wheaton WD, Zimmer SM, Grefenstette JJ, Bailey RR, Assi T-M, Burke DS
JournalVaccine
Volume28
Issue31
Pagination4875-9
Date Published2010 Jul 12
ISSN1873-2518
KeywordsChild, Computer Simulation, Disease Outbreaks, Health Care Rationing, Humans, Influenza A Virus, H1N1 Subtype, Influenza Vaccines, Influenza, Human
Abstract

In the fall 2009, the University of Pittsburgh Models of Infectious Disease Agent Study (MIDAS) team employed an agent-based computer simulation model (ABM) of the greater Washington, DC, metropolitan region to assist the Office of the Assistant Secretary of Public Preparedness and Response, Department of Health and Human Services, to address several key questions regarding vaccine allocation during the 2009 H1N1 influenza pandemic, including comparing a vaccinating children (i.e., highest transmitters)-first policy versus the Advisory Committee on Immunization Practices (ACIP)-recommended vaccinating at-risk individuals-first policy. Our study supported adherence to the ACIP (instead of a children-first policy) prioritization recommendations for the H1N1 influenza vaccine when vaccine is in limited supply and that within the ACIP groups, children should receive highest priority.

DOI10.1016/j.vaccine.2010.05.002
Alternate JournalVaccine
PubMed ID20483192
PubMed Central IDPMC2906666
Grant List1U54GM088491-0109 / GM / NIGMS NIH HHS / United States
U54 GM088491 / GM / NIGMS NIH HHS / United States
U54 GM088491-01 / GM / NIGMS NIH HHS / United States
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