Economics of influenza vaccine administration timing for children.

TitleEconomics of influenza vaccine administration timing for children.
Publication TypeJournal Article
Year of Publication2010
AuthorsLee BY, H Y Tai J, Bailey RR, Smith KJ, Nowalk AJ
JournalAm J Manag Care
Date Published2010 Mar
KeywordsAdolescent, Age Factors, Child, Child, Preschool, Computer Simulation, Cost-Benefit Analysis, Decision Support Techniques, Female, Humans, Immunization Schedule, Influenza A Virus, H1N1 Subtype, Influenza Vaccines, Influenza, Human, Male, Monte Carlo Method, Quality-Adjusted Life Years, Seasons, Sensitivity and Specificity, Time Factors, Vaccination

OBJECTIVES: To determine how much should be invested each year to encourage and operationalize the administration of influenza vaccine to children before November and how late the vaccine should be offered each year.STUDY DESIGN: Monte Carlo decision analytic computer simulation models.METHODS: The children's influenza vaccination timing model quantified the incremental economic value of vaccinating a child earlier in the influenza season and the incremental cost of delaying vaccination. The children's monthly influenza vaccination decision model evaluated the cost-effectiveness of vaccinating versus not vaccinating for every month of the influenza season.RESULTS: Getting children vaccinated by the end of October rather than when they are currently getting vaccinated could save society between $6.4 million and $9.2 million plus 653 and 926 quality-adjusted life-years (QALYs) and third-party payers between $4.1 million and $6.1 million plus 647 to 942 QALYs each year. Decision makers may want to continue offering influenza vaccination to children at least through the end of December. Vaccinating with trivalent inactivated virus vaccine was more cost-effective than vaccinating with live attenuated influenza vaccine for every month.CONCLUSION: Policymakers could invest up to $6 million to $9 million a year to get children vaccinated in September or October without expending any net costs.

Alternate JournalAm J Manag Care
PubMed ID20205492
PubMed Central IDPMC3763213
Grant List1U54GM088491-0109 / GM / NIGMS NIH HHS / United States
R01 LM009132 / LM / NLM NIH HHS / United States
SR01LM-009132-02 / LM / NLM NIH HHS / United States
U54 GM088491 / GM / NIGMS NIH HHS / United States
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