Constructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles.

TitleConstructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles.
Publication TypeJournal Article
Year of Publication2010
AuthorsLee BY, Burke DS
JournalVaccine
Volume28
Issue16
Pagination2806-9
Date Published2010 Apr 1
ISSN1873-2518
KeywordsHumans, Product Surveillance, Postmarketing, Vaccines
Abstract

As history has demonstrated, post-approval obstacles can impede a vaccine's use and potentially lead to its withdrawal. Addressing these potential obstacles when changes in a vaccine's technology can still be easily made may improve a vaccine's chances of success. Augmented vaccine target product profiles (TPPs) can help vaccine scientists better understand and anticipate these obstacles and galvanize conversations among various vaccine stakeholders (e.g., scientists, marketers, business development managers, policy makers, public health officials, health care workers, third party payors, etc.) earlier in a vaccine's development.

DOI10.1016/j.vaccine.2009.09.047
Alternate JournalVaccine
PubMed ID19782109
PubMed Central IDPMC3385993
Grant ListU01 GM070708 / GM / NIGMS NIH HHS / United States
U54 GM088491 / GM / NIGMS NIH HHS / United States
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